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Just wanted to chime in. There are some cases where memory cleaner and others are VERY useful. If you are using media editing or recording software (think Final Cut Pro, Logic, etc...) they can use large amounts of RAM as soon as you execute a rendering or recording command. While OSX does manually manage the File Cache memory well, it is not always fast enough to do it before the app makes a huge demand on the resource and can crash or freeze up the app. I typically only use it for this reason. Just before recording or rendering I tell it to clean the memory, which empties the file cache and prevents my Final Cut or Logic from crashing or freezing. SO, you are right in that most people don't need memory cleaners, but there are cases where it can be very useful.